Adobe CS5 uses Camera Raw, that might have a better RAW processing than ACDSee. What version of it are you using?
It's not abnormal to observe that. For example, Aperture 3 handles noise better than Aperture 2 did, all my high ISO shots with my old Nikon D50 just got better in 2010

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"Those who cannot remember the past are condemned to repeat it."
Santayana, George.
The Life of Reason, Reason in Common Sense, Scribner's, 1905, page 284
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