Brooklyn Brewery. Be forewarned, the beer is good but it's not Deschutes Nitro drawn Obsidian Stout. I've had that precious nectar only once in my life. Drove up 17 hours from the LA area to visit friends in the Portland area and we went to the Deschutes brewery in Bend. Mmmm.
I used to live on Whidbey Island.
I digress.
There are great pubs around but if you want local beer, I'd say the Brooklyn Brewery is your ticket.
You might want to get this posted or cross-posted in the NYC RFF club forum as well. We like beer. And photography stuff.
EDIT: I completely got sidetracked by beer talk. As for galleries to check out, all I can offer right now is the Leica Gallery at 670 Broadway. Then there's always the MOMA, Metropolitan Museum, and a few other big ones.
Phil Forrest